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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b6f970f67b0e5ad893d9bca1968cb2bdf1cce388108e73d04e80de5eea0a7e05' 
  AND token = 'li9uhKrxQcwzTD1EtCuBWaiPJHy2+/PCs1MJiPf1Xik=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}