SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7af8f89e2bec523a0e662d9354206f31f1867a823f186eadcba3048a1a1f8a7d' 
  AND token = 'ZQeGO0K77aAdN733NnzrH3tcmd6I3JOtXHEnpPGcuAg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}