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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66d0b7a81637f8810f6ff9d351257daa0e30bf5f022f6fe1f28d4616584d693a' 
  AND token = 'GHv2TNmu2M0NsaWDdKquhiGoN/+Ae0SNF7E41JeFwIA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}