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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1e2d9d57cdf3f75be1dba8fd786edfcbf4aecf21f9bd70a55af0a09e0ed925d' 
  AND token = '4GIo1l/Cu/uy74Vs19uXxdsGavKhQ2Gebcw4JZfxFAA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}