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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e20ae6923c31721acc7f0a761fcbb8502615a1ec99397ab303f869efc06af59' 
  AND token = 'FRaLUxkptWAgz44PLEL1fO6juQWoGi5GaT7KyflGqdE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}