SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3a8c99772f6b720a4edcbaf829b3c497c3487825ab5354bcf02f906c85ad686' 
  AND token = 'Hzi6MmTno+wU9+NYs1mRcs8QsyPH+WD5VHKOd9czxwA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}