SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be9d96fd2300fef79aa0baff2906589d66254b813268fb3271ae8fed8aeb3feb' 
  AND token = 'UArL7I4gEt3RE+gnFOa9zlJAirACoipttOLXgUoIoQ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}