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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '825c67dca3639244d3ef6089c8ddf0d0e7f5cbc2181f541947509a784e660b81' 
  AND token = '+dpbfqMuZacc2HoKqYsWKMiCkxn89iI215A7UZRp+V8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}