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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2678503876b111372bd315eb83ea8dd267b75d37386c0853268c1dfb6182a3b1' 
  AND token = 'vW8DzEMW945mGz16AviwxrgrsKH4VpWuk5sYYM4VvpU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}