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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c6ad67e8c2924d3e214c5af9991ad2a1b94302b92638db01ea9565cdef0f255' 
  AND token = 'NMDgU7IKrBaeLq+7R57zw7RK8EQ0NO+1Qzhaoyi/W0s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}