SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b1a6de5d5a143aa01c7b52cecc03a98b30105ee71ca47312c136e9e77351818b' 
  AND token = '8jYIDwrgLKrRunALfYcRhiF+WhoomTbeivs+w4GDWP0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}