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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f70afeeb875d89d963e4aa31e242b90520ee8b19171227a274b8c99bdd2c17a1' 
  AND token = '2vANC+0A9/GPpGTOS4TQdeEkVnTzF4HeSdSx7L4uUHg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}