SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7906d1246886973205818456eccdfdde3067c20294d11850904e663461416b7b' 
  AND token = 'T/ZYR7SqIOM7IvFTZ2AfDRS/VAiy04q/hIPylzyVvNA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}