SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f153e67604c544f0cbaaa565fd84d925e24072a8e41d33448aab9b209b616a93' 
  AND token = 'oSgyRfK/Ep4rR36MkzyMbB4T8fLh1Aye4U+0+8yM2MM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}