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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ff6c42ac728a244fd06dc5220a102fba3df00b28d65dbe60db70f165cd60fc0' 
  AND token = 'loWHJ0K6pqbkM2DwGuOAkOEy2x2RyGZI3y9/cBs63Po=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}