SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a57bfad02dcf6598238b433d1080f9c20c50e3cebfaf140a33ece63b619c8169' 
  AND token = '2gsRsUIHxxbnIeTkSvGmDR7w9xs6r4C0jGzxXShQhA4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}