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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5c6eccbc57090170682d2c0c0abeba57c75e087ad21ad5bb6cba47a018a7444' 
  AND token = 'XvAUnaJjJ/aOlc+LEc21NasVCfBzz/Y+hBv1Bp/bbC8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}