SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c348d5cb319d1035122d873126dfabf2c45a14d1fe4341212c74e0cd184e01b6' 
  AND token = 'BOyNGJ6/PwdsXLWSyPR9n65QIs4VarggHJo2QXmb9EU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}