SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a25ed9e6e5d0e889c5490e01de86e0befe8b12352990de0dd206ac7012883746' 
  AND token = 'n4jS1OS2tQ35hrWCQGeGPIw6xmWi3h5ptRRjJXPx4x4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}