SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3238b62d23e41820c7e72df17df0951a0b1921019e00dbda36bb8986e85c1a6e' 
  AND token = 'XeXrRnuAtG8F7M9qzYjn9stOIPUEyb/NiY6pBdqxaKU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}