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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '70e0c6659c79a0cf4d23f2fd507aa2506697b661f1e3f2dcef71ea58b8444d53' 
  AND token = 'N2fAXiBrCP2hTOSWvmhnvDkivIueh0gj1EsjD/yuOnI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}