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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78a89aefd5965e5d8da26c19df068e3ce5f9a33feec980ef617b8d9601c1231f' 
  AND token = 'aE8qOiRLGl/CL2Slh1MkswWNyt9isoKwUrR2cvXzakA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}