SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d17a979dd3d2f6be32c5cc2599e85e2538de6af2e15ffdac08881602b00afcb' 
  AND token = 'E8wk4LU1hx5qx7Y9uElqoKVBBNuPJE+JhEEEfLRo10A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}