SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a69e0c9fdc32d1561ed200c7dc696b43a1f4d8fdfda195a2cec8086118700a0' 
  AND token = 'AcnApsBWNXcqG+W74bSbwN7z5+WjXwIYFTTD1Y9nEhs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00056

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}