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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '459879c7c5aa9538aa2a9976319265f9c57a783daf83e9ad00ed845595f1df3f' 
  AND token = '7d9GRWsGtcfvbnUTQL8sVAWxuTfC4a8JRlCk1PBOvaA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}