SELECT 
  product_id, 
  feature_id, 
  variant_id 
FROM 
  cscart_product_features_values 
WHERE 
  product_id IN (
    279427, 279428, 279429, 279430, 279431, 
    279432, 279433, 279434, 279435, 279436, 
    279437, 279438, 279439, 279440, 279441, 
    279442, 279443, 279444, 279445, 279446
  ) 
  AND feature_id IN (1004) 
  AND lang_code = 'en'

Query time 0.00170

JSON explain

{
  "query_block": {
    "select_id": 1,
    "cost_info": {
      "query_cost": "9.06"
    },
    "table": {
      "table_name": "cscart_product_features_values",
      "access_type": "range",
      "possible_keys": [
        "PRIMARY",
        "fl",
        "lang_code",
        "product_id",
        "fpl",
        "idx_product_feature_variant_id"
      ],
      "key": "lang_code",
      "used_key_parts": [
        "lang_code",
        "feature_id",
        "product_id"
      ],
      "key_length": "12",
      "rows_examined_per_scan": 20,
      "rows_produced_per_join": 20,
      "filtered": "100.00",
      "using_index": true,
      "cost_info": {
        "read_cost": "5.06",
        "eval_cost": "4.00",
        "prefix_cost": "9.06",
        "data_read_per_join": "15K"
      },
      "used_columns": [
        "feature_id",
        "product_id",
        "variant_id",
        "lang_code"
      ],
      "attached_condition": "((`webmarco`.`cscart_product_features_values`.`feature_id` = 1004) and (`webmarco`.`cscart_product_features_values`.`product_id` in (279427,279428,279429,279430,279431,279432,279433,279434,279435,279436,279437,279438,279439,279440,279441,279442,279443,279444,279445,279446)) and (`webmarco`.`cscart_product_features_values`.`lang_code` = 'en'))"
    }
  }
}

Result

product_id feature_id variant_id
279427 1004 64478
279428 1004 64484
279429 1004 64485
279430 1004 64486
279431 1004 64487
279432 1004 64488
279433 1004 64489
279434 1004 64490
279435 1004 64491
279436 1004 64492
279437 1004 64493
279438 1004 64494
279439 1004 64495
279440 1004 64496
279441 1004 64497
279442 1004 64479
279443 1004 64480
279444 1004 64481
279445 1004 64482
279446 1004 64483