SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dcf21266c44032d6fff5510ae53fdff00d9c5bcb108c7f12f773dd110921c251' 
  AND token = 'aD9Eh00Ohin29T0/PPc6L+zw6ikOMI5mqtDg2in2CI4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}