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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9fe0a43bc44791e53327efc1af11281e176887d7a0f271c1adc75a9590dd05f8' 
  AND token = 'b2JIPU1JTsN9f/nQ/Qp1xbkAQBYf6NpN5YmsoIAVdLY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}