SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a27227a157e40ee1bfd7ef183203a061feea893601e7c81ed774bf44237ba8d0' 
  AND token = 'WDWUtb9OnkfCwfrmsFdEjhaUJhXFYioaJg25JZ2BoxI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}