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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48252656ffc3234c97d87f085089e36c58cd0c11a18d02bd93bf385673b16645' 
  AND token = 'u7Ey2a4M7p+3Pj1rg4cBtwZqQWeTsXG9VduV4woFVnw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}