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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f3e8060630393c8bc95fd23d87f0c025b1e01e990e75bb51c5fb41ac5b10442' 
  AND token = 'w5TY1O6ejXvfEyr+EpCTgPktnZQdCCBHMa6cV+9I1XQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}