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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b0002dcb193021f98e02dad44abcd55f8d1218ca1f9379a761f49ed74da0ef4' 
  AND token = '3eE07Xambwy68a5655P+dZ2hWX9x7oc5pzcv+6TkjGI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00075

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}