SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04de380cdd2b51b5f6fa0893db0a6bc1b0276c8f6b197f4a372d1888b5528f4b' 
  AND token = 'UNGMTfnkRe3nJFLwOSwsBfv8aVqMYQryjeXUr9r9pEk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}