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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2454bc0666f9460776209f0906a13b4783b288466f4f0011513d8aa68e4aae0' 
  AND token = 'dKquCf5nhmVolywsSnPpVXDOX3v8ngxFy5uEsj70/Cg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}