SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '601335d5fdd08036d9ad733101576c2b3aa91b09f4debfc1d291447f7b049a34' 
  AND token = 'AS0RfH4k0g4paBvMuGjw8Lz+QJQAe8IfyR+M2Y+DKMI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}