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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ab5cc4fe84aaa0359f303baabbf7f1ce2d9b2559264d71a90ff97fee31427b4b' 
  AND token = 'CrwBOjRPnrpTO9iH/lqh5y06zCFPSd4pXMPmzj9yYRA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}