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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e2ab96d83aea239eb24d0736959a2dce962a92ab85a0df1accdbce6b0003278' 
  AND token = '1UmkoYDArBEegpxNR58qOcsS4+smIA44RkbDPBvfGZo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}