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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e1ddcb4ac18d764871ae459eec3558a314558f2f7bf7ffcafb9dace56f21f18' 
  AND token = 'Uo/DsxG4PK7eQO1OkKTA86/CCH32soDAqUEedVYW5Ec=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}