SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '488d8b3a3647230385b8183b0614f87b993e18e7f93de722239b59b32a40616d' 
  AND token = 'yv8165qJLSNmdUOS8dxGlcPxQ1I6CLUTmgNFcr5c7uw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}