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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8fc32d1ed09eb26029e7cd20f74af7bb0605187854df39760857d828afaf1298' 
  AND token = 'm3EQGq4CFbyG02IQQEHxoDSETyRloxPLh2OOsfAA5ZM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00060

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}