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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75918270ecf1dadbb9aafb653dec57432fb90b3b81b04fa737c82bf05e02b2a2' 
  AND token = 'JBLC3KE3TwKFCHTU2SOG3HcP+9k0Mpuf40Azh0o3YEU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}