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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df3f5b270b2fd5621a7575abd9f28d3484479d4ccc3dcf8b36e76ec0fe5de50d' 
  AND token = 'p1Y40KD8xGSvPT2BduUcvnKumLrZ61lM7yobtZsFdVE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}