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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3fb33a1bdaf72eea8185f7facf5b94f2c0d514121ee8be422d4b7d915dc02a03' 
  AND token = '7CA1OYi+ru1vjvHjdchf4w2pCAXI/e6uAmZIZvEb/I4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}