SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1b43672ab0467b26b7a05174e25996db5ba3276ad90a7bf4332d94442274998' 
  AND token = 'EaG4IFj3TozhagfD301c0/J7dlbnJydONAbQeLzIVpg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}