SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27fa4ed9b268f35aa01e7ca3f7d322096ab1d8795983b0a3f751c8dd6805d58e' 
  AND token = 'QCgZ0Ime3UPKFG/h8xKpaeGSNFIiAMgnAbgRnbC1Xno=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}