SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c5c1d7b326d0e570aaf70af2312deae3b59bb5315b64f82f6c888b24f39bbbc' 
  AND token = 'bXo+IMiIABQ5P/FYaQqbo6+IW4AOovI92Bvli9zAbOs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00056

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}