SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0df216b0e578a76cc3a77af04672dc7b58778fb5130a494919421dbe0a4090a' 
  AND token = 'IArn7zNUcE9HRMHx6KIhx1aHsPpk4pZJfCUD2h1BKww=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}