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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39fb527ed5b5dd662b781482792b684a8bf4e3fafd6358d93c09588f402ffb53' 
  AND token = 'A8Fu24H3ZXG4+bET2StH0ezQ0rLmZKC4dwMfusdhQ3s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}