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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd6c366bddfa697f2090131b4e285fc3ac4472e2b22b652a89cee38ecac065afe' 
  AND token = 'v3FjklCV7pJE/IYIeNx1rOS1j2M8GWoPmgkoBnT5IxI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}