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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e8c2e22d75bb64ce9f5a5fc54154e062740272dcfbd3901f0dbf998a0c5c2b5' 
  AND token = 'XyyFmqXV3Gdn0pxQjCuOgvvMWoe0+UfGwHlk03Ky7go=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}